Association between p53 codon 72 polymorphism and systemic lupus erythematosus
نویسندگان
چکیده
منابع مشابه
Codon 72 Polymorphism of p53 Gene and Hematologic Manifestations in Patients with Systemic Lupus Erythematosus
Background: Systemic lupus erythematosus is a systemic autoimmune disorder with unclear etiology. The importance of some genes in the development of systemic lupus erythematosus has been implicated. The gene polymorphism in codon 72 has attracted a lot of attention and its role in the occurrence or progression of many cancers and autoimmune diseases especially systemic lupus erythematosus has ...
متن کاملcodon 72 polymorphism of p53 gene and hematologic manifestations in patients with systemic lupus erythematosus
background: systemic lupus erythematosus is a systemic autoimmune disorder with unclear etiology. the importance of some genes in the development of systemic lupus erythematosus has been implicated. the gene polymorphism in codon 72 has attracted a lot of attention and its role in the occurrence or progression of many cancers and autoimmune diseases especially systemic lupus erythematosus has b...
متن کاملAssociation between p53 Codon 72 (Arg72Pro) Polymorphism and Primary Open-Angle Glaucoma in Iranian Patients
Background: Glaucomatous neuropathy is a type of cell death due to apoptosis. The p53 gene is one of the regulatory genes of apoptosis. Recently, the association between the p53 gene encoding for proline at codon 72 and primary open-angle glaucoma (POAG) has been studied in some ethnic groups. This study is the first association analysis of POAG and p53 codon 72 polymorphism in Iranian patients...
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Histiocytic necrotizing lymphadenitis or Kikuchi's disease is a rare, benign condition of unknown etiology, which is usually characterized by cervical lymphadenopathy and fever. This disease is rarely associated with systemic lupus erythematosus. Here we describe, for the first time in Iran, a patient who developed systemic lupus erythematosus about 3 years after the initial diagnosis of Kikuch...
متن کاملparaoxonase (pon1) 55 polymorphism and association with systemic lupus erythematosus.
paraoxonase-1 (pon1) is a serum hdl-bound enzyme that hydrolyzes a number of aromatic carboxylic acid esters including lipid peroxides, preventing ldl oxidation. systemic lupus erythematosus (sle) patients are at greater risk of oxidative stress, which is associated with abnormal plasma lipid metabolism. in this study, association of pon-55 polymorphism with serum arylesterase (are) activities,...
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ژورنال
عنوان ژورنال: Reumatologia/Rheumatology
سال: 2014
ISSN: 0034-6233
DOI: 10.5114/reum.2014.42794